Association between dietary fat content and outcomes in pediatric burn patients

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Reference Type:
Journal Article
Accession No.:
Journal of Surgical Research
Year, Volume, Issue, Page(s):
2011, vol. 166, issue 1, pp e83-390
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Study compared a low fat/high-carbohydrate diet and a high-fat diet on morbidity and mortality outcomes in severely burned children. Nine hundred forty-four children with burns on 40 percent or more of their total body surface area (TBSA) were divided into two groups: 518 patients receiving Vivonex T.E.N. (low-fat/high-carbohydrate diet) and 426 patients receiving milk (high-fat diet). Patient demographics, caloric intake, length of hospital stay, and incidence of sepsis, mortality, hepatic steatosis, and organomegaly at autopsy were determined. Demographics and caloric intake were similar in both groups. Patients receiving Vivonex T.E.N. had shorter intensive care unit (ICU) stays, a shorter ICU stay per percentage TBSA burn, a lower incidence of sepsis, and lived significantly longer until death than those receiving milk. There was no difference in overall mortality between the two groups. Autopsies revealed decreased hepatic steatosis and decreased enlargement of kidney and spleen in patients receiving Vivonex T.E.N. Results suggest the benefit of high carbohydrate/low fat nutrition; however, the findings in these time periods can also be likely due to the multifactorial effects of advances in burn care. The authors believe that these results have some relevance because high fat is associated with poorer outcomes compared with low fat.
Lee JO, Gauglitz GG, Herndon DN, Hawkins HK, Halder SC, Jeschke MG
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