Relationships among pemorbid alcohol use, acute intoxication, and early funcational status after traumatic brain injury

Short Title:
Relationships among pemorbid alcohol use, acute intoxication, and early funcational status after traumatic brain injury
Model System:
TBI
Reference Type:
Journal Article
Accession No.:
Journal:
Archives of Physical Medicine and Rehabilitation
Year, Volume, Issue, Page(s):
2008, vol. 89, issue 1, pp 48-55
Publication Website:
Abstract:
OBJECTIVE: To investigate the relationships among intoxication at time of injury, preinjury history of problem drinking, and early functional status in patients with traumatic brain injury (TBI). DESIGN: Prospective cohort study. SETTING: Acute inpatient TBI rehabilitation. PARTICIPANTS: Participants were 1748 persons with TBI. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Blood alcohol levels (BALs) were obtained at admission to the emergency department, and a history of problem drinking was obtained through interview. Study outcomes, Disability Rating Scale (DRS), and FIM instrument scores were gathered at admission to inpatient rehabilitation. RESULTS: Multivariate regression analysis revealed that BAL and a history of binge drinking were predictive of DRS, but not FIM, scores. A higher BAL was associated with poorer functional status on the DRS. Paradoxically, a history of binge drinking was associated with more intact functional status on the DRS. CONCLUSIONS: The relationships among intoxication at time of injury, history of problem drinking, and early outcome after TBI were modest. Injury severity had a more significant association with TBI functional status.
Author(s):
Vickery, C.; Sherer, M.; Nick, T.; Nakase-Richardson, R.; Corrigan, J.; Hammond, F.; Macciocchi; Ripley, D.; Sander, A.
Author Address(es):
Chad D. Vickery, PhD, Methodist Rehabilitation Center, 1350 E Woodrow Wilson, Jackson, MS 39216

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