Magnetic resonance imaging of traumatic brain injury: Relationship of T2 SE and T2* GE to clinical severity and outcome

Short Title:
Magnetic resonance imaging of traumatic brain injury: Relationship of T2 SE and T2* GE to clinical severity and outcome
Model System:
TBI
Reference Type:
Journal Article
Accession No.:
J46586.
Journal:
Brain Injury
Year, Volume, Issue, Page(s):
2004, vol. 18, issue 11, pp 1083-1097
Publication Website:
Abstract:
Study compared the sensitivity of T2-weighted gradient echo (T2* GE) magnetic resonance imaging (MRI) with T2 fast spin echo (T2 SE) MRI for detecting lesions and defining lesion patterns resulting from traumatic brain injury (TBI). It also examined the relationships of different traumatic lesion patterns to clinical indicators of injury severity and 1-year post-injury outcome measures. Forty-three patients with TBI were imaged using T2 SE and T2* GE techniques an average 26 days after injury. Acute clinical severity measures were abstracted from medical records. One-year post-injury outcome measures included the Glasgow Outcome Scale, the Disability Rating Scale, and the Craig Handicap Assessment and Reporting Technique-Short Form. Results showed that T2* GE detected significantly more lesions in each of the cortical, white matter, central grey, and brainstem regions and in each of the frontal, temporal, parietal, and occipital lobes, compared to T2 SE. T2* GE was more sensitive for detecting lesions, particularly petechial lesions. Both the T2 SE and T2* GE findings were predictive of all three 1-year outcome measures.
Author(s):
Gerber, Donald J.; Weintraub, Alan H.; Cusick, Christopher P.; Ricci, Peter E.; Whiteneck, Gale G.
Author Address(es):

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