Mortality after discharge from acute care hospitalization with traumatic brain injury: a population-based study

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Journal Article
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Year, Volume, Issue, Page(s):
2010, vol. 91, issue 1, pp 20-29
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Study examined long-term mortality after acute hospitalization for traumatic brain injury (TBI) among patients from diverse races, ethnicities, and socioeconomic conditions. Data were collected for 18,998 Colorado residents with TBI discharged alive from acute hospitalization between 1998 and 2003. Vital status at the end of the study period and statewide population mortality rates were used to calculate all-cause and cause-specific standardized mortality ratios (SMRs) and life expectancy compared with population mortality rates. The influence of demographics, injury severity, and comorbid conditions on time until death was investigated using age-stratified Cox proportional hazards modeling. Results indicated that patients with TBI carried about 2.5 times the risk of death compared with the general population. Life expectancy reduction averaged 6 years. SMRs were largest for deaths caused by mental/behavioral and neurologic conditions and were smaller but significantly higher than 1.0 for an array of other causes. Injury severity and older age increased mortality among young people (age under 20 years). However, risk factors for mortality among adults age 20 and older involved multiple domains of demographics (metropolitan residence), injury-related measures (falls versus vehicular incidents), and comorbidity (3 or more comorbid health conditions versus none).
Ventura T, Harrison-Felix C, Carlson N, Diguiseppi C, Gabella B, Brown A, Devivo M, Whiteneck G.
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