Hydrophilic catheters versus noncoated catheters for reducing the incidence of urinary tract infections: a randomized controlled trial

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Journal Article
Accession No.:
Archives of Physical Medicine and Rehabilitation
Year, Volume, Issue, Page(s):
2009, vol. 90, issue 10, pp 1668-71
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Objective: To test the hypotheses that hydrophilic catheters reduce the incidence of symptomatic urinary tract infections (UTIs) in persons with spinal cord injury on self-intermittent catheterization (IC). Design: Randomized controlled trial. Setting: Community. Participants: Subjects (N=56) on IC with recurrent UTIs and who met eligibility cIitelia. Intervention: Use of hydrophilic catheters for rc. Main Outcome Measure: Symptomatic UTIs treated with antibiotics. Results: Of the 56 subjects enrolled, 45 completed the study (22 in the b-eatrnent group, 23 in the coutrol group). There were 110 significant differences in demographics, including sex, between the treatment group and the controls except for more tetraplegic subjects in the control group (P<.05). Seventy-one percent of the treatment group and 52% of the control group were men. The total number of symptomatic UTls treated with antibiotics was significantly smaller in tIle treatment group than in the control group (P<.05). Seventy percent of the control group had at least 1 antibiotic treatment episode compared with only 50% of those with the hydrophilic catheter (P=.18). There was "no significant difference in the incidence of bacteriulia or symptomatic UTls among the 2 groups. Level of injury and years with injury were unrelated to symptomatic UTIs, but being female increased the Iisk of UTls (P<.Ol). Conclusions: Although there was DO difference in the number of symptomatic UTls in the 2 groups, hydrophilic catheter usage was associated with reduced numbers of treated UTIs as compared with standard nonhydrophilic catheters in persons with spinal cord injnry who used self-IC; however, the study is limited by a small sample size. Women on self-Ie were more likely to develop UTIs regardless of the catheter type, suggesting that the benefits of the lublication may be more important in men. Key Words: Rehabilitation; Spinal cord injuIies; Urinary catheterization; Urinary tract infections.
Cardenas D, Hoffman J
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