Gabapentin in the treatment of neuropathic pain after spinal cord injury: A prospective, randomized, double-blind, crossover trial

Short Title:
Gabapentin in the treatment of neuropathic pain after spinal cord injury: A prospective, randomized, double-blind, crossover trial
Model System:
SCI
Reference Type:
Journal Article
Accession No.:
J45949.
Journal:
Journal of Spinal Cord Medicine
Year, Volume, Issue, Page(s):
2002, vol. 25, issue 2, pp 100-105
Publication Website:
Abstract:
Study evaluated the effectiveness of gabapentin in the treatment of pain for patients with spinal cord injury (SCI). Patients were randomly assigned to a 4-week course of either treatment with gabapentin or placebo, followed by a 2-week washout period. At the beginning of the seventh week, patients who had received gabapentin initially were switched to the placebo and the placebo group then received gabapentin for 4 weeks. Pain levels were monitored and recorded throughout the 10-week study period. Results showed a significant decrease of "unpleasant feeling" and a trend toward reduction of "pain intensity" and "burning sensation" by the fourth week of gabapentin treatment compared to the placebo treatment.
Author(s):
Tai, Qing; Kirshblum, Steven; Chen, Boqing; Millis, Scott; Johnston, Mark; DeLisa, Joel A.
Author Address(es):

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