Effect of intrathecal baclofen bolus injection on temporospatial gait characteristics in patients with acquired brain injury

Short Title:
Effect of intrathecal baclofen bolus injection on temporospatial gait characteristics in patients with acquired brain injury
Model System:
TBI
Reference Type:
Journal Article
Accession No.:
J49019.
Journal:
Archives of Physical Medicine and Rehabilitation
Year, Volume, Issue, Page(s):
2005, vol. 86, issue 6, pp 1127-1133
Publication Website:
Abstract:
Computerized gait analysis was conducted to evaluate changes in temporospatial gait characteristics after intrathecal baclofen (ITB) bolus administration in patients with spasticity resulting from acquired brain injury (ABI). Walking performance and spasticity in lower-extremity muscles were assessed before and at 2, 4, and 6 hours after ITB bolus injection. Gait analysis data was used to calculate the following temporospatial gait parameters: (1) velocity, (2) stride length, (3) cadence, (4) step symmetry, (5) step width, (and 6) percentage of gait cycle spent in single-limb support phase. Results showed that although ITB bolus injection consistently reduced spasticity in patients with ABI, it does not necessarily result in improved walking performance. While the majority of subjects showed improvement in velocity, stride length, and step width, some subjects either worsened or remained unchanged.
Author(s):
Horn, Terry S.; Yablon, Stuart A.; Stokic, Dobrivoje S.
Author Address(es):
Participating Centers:

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