Fracture threshold and risk for osteoporosis and pathologic fractures in individuals with spinal cord injury

Short Title:
Fracture threshold and risk for osteoporosis and pathologic fractures in individuals with spinal cord injury
Model System:
SCI
Reference Type:
Journal Article
Accession No.:
J49130.
Journal:
Topics in Spinal Cord Injury Rehabilitation
Year, Volume, Issue, Page(s):
2005, vol. 11, issue 1, pp 61-69
Publication Website:
Abstract:
Article defines the fracture threshold at the knee, examines mechanisms of bone injuries, and identifies risk factors for osteoporosis and bone fracture in people with spinal cord injury (SCI). Fracture threshold refers to the level of bone mineral density (BMD) in a specific site below which most fractures occur. Using the knee as a proxy for the entire lower extremity, fractures in the LE begin to occur when the BMD at the knee is .86 gm/cm squared (-25 percent loss) and peak at .49 gm/cm squared (-57 percent loss). The BMD fracture threshold at the knee was found to be .78 gm/cm squared (-36 percent loss), while the BMD breakpoint was found to be .49 gm/cm squared (-57 percent loss). Risk factors for fracture and osteoporosis include completeness of injury, paraplegia, body mass index, increasing age, duration of injury, female gender, and previous fracture.
Author(s):
Garland, Douglas E.; Adkins, Rodney H.; Stewart, Charles A.
Author Address(es):
Participating Centers:

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